Workshop on Diagnostic Test Methods

Background:
This course provides exhaustive knowledge in the principles and practice of Diagnostic tests to comprehend reliability and validity of a new diagnostic test, the biases and the challenges in designing a study and, critically evaluate a diagnostic study article. This course will also cover the basics of quality control methods in a laboratory. This course will include lectures and comprise a series of practical.

Course Objectives:

  • The learn the concept of what is disease
  • To learn the diagnostic thinking process and the phases of development of diagnostic tests
  • To understand the principles of Validity and Reliability
  • To be competent in calculating and interpreting diagnostic statistics, sensitivity, specificity, PPV,NPV
  • To understand the concept of Bayesian thinking and the basic Bayesian formula
  • To be able to calculate and interpret Likelihood ratios as well as post test probabilities
  • To be able to interpret serial and parallel tests
  • To understand the concepts of ruling in or ruling out disease with respect to ideal cut-off points
  • To learn ROC curves-principles and interpretation
  • To interpret screening tests and their use and pitfalls
  • To be able to critically appraise an article on Diagnostic test accuracy
  • To be able to understand the concept and critically appraise a diagnostic systematic review
  • To introduce the concept of health technology assessment

Who should apply?
This course is tailored to medical college faculty who are post, allied health professionals, nonmedical faculty, and/or researchers actively involved in diagnostic test research (validity and reliability studies), or teaching institution or in furthering their knowledge and skills in methodology.

WHOM:
The target audience is Government medical college doctors who are post MD/MS, teaching faculty.

Venue:
The Stem Cell Research Center,
Christian Medical College,
Bagayam,
Vellore, Tamilnadu,
India.

For registration, click here

HOW:
1. The number of participants will be 30
2. The application process is online and can be accessed from the CEU CMC Vellore website, www.clinepi.cmcvellore.org/ or the BVMC website, www.bvmc.in. The last day for applying online is 15/11/2019 before 6 PM.
3. Eligibility criteria

  • Confirmed faculty of a Government medical college in India
  • Assistant/ Associate or Professor level
  • Should write a short note on how this workshop will benefit the participant and their teaching of students
  • The applications will be scrutinized by the CDSA-CMC team and the final list of 30 participants will be informed by 18/11/2019.
  • Train travel (3rd AC, local transport, Shared accommodation, workshop material and food expenses for the 3 days will be taken care of by CDSA

Workshop Content

  • Research questions and study designs
  • What is disease?
  • How do we diagnose?
  • Diagnostic Study Designs-Phases
  • Tests as part of a clinical pathway
  • Types of Validity & Reliability
  • The Diagnostic studies Statistics: SN, SP, PPV NPV, Effect of prevalence
  • Diagnostic odds P value and LR, Bayesian
  • Indeterminate, Intermediate, un-interpretable results
  • Bias in diagnostic study including Spectrum Bias, Verification Bias
  • Critical appraisal
  • Sample size calculation
  • Parallel and Multiple tests
  • Philosophy of ROC
  • How to construct ROC Curve
  • Choosing he ideal cut-off points Using LR, ROC
  • Comparing two tests using ROC Curve
  • Economics and diagnostic tests, Health tech assessment
  • Systematic Reviews of diagnostic studies and MA
  • Diagnostic SR critical appraisal

FACULTY:

The faculty for the course includes renowned epidemiologists, statisticians and physicians trained in clinical epidemiology from CMC, Vellore. The detailed list of faculty and the complete brochure is available here